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Comparison of home ambulatory type 2 polysomnography with a portable monitoring device and in-laboratory type 1 polysomnography for the diagnosis of obstructive sleep apnea in children
Journal of Clinical Sleep Medicine ( IF 4.3 ) Pub Date : 2021-07-29 , DOI: 10.5664/jcsm.9576
Adelaide Withers 1, 2, 3, 4 , Jennifer Maul 1 , Ellen Rosenheim 5 , Anne O’Donnell 1 , Andrew Wilson 1, 2, 4, 6 , Prof Stephen Stick 1, 2, 3, 6, 7
Affiliation  

Study Objectives:

To compare type 2 polysomnography (T2PSG) to the gold standard type 1 in-laboratory polysomnography (T1PSG) for diagnosing obstructive sleep apnea (OSA) in children; validate home T2PSG in children with suspected OSA.

Methods:

81 participants (ages 6-18) with suspected OSA had simultaneous T1PSG and T2PSG in the sleep laboratory, 47 participants (ages 5-16) had T1PSG in the sleep laboratory and T2PSG performed at home. Sleep scientists staged and scored PSG data, pediatric sleep physicians assigned a diagnosis of normal or OSA. Participant demographics, PSG variables and diagnoses were compared using Chi-Squared and Fischer’s exact tests for nominal variables, t-test for continuous variables and Cohen’s kappa to assess concordance.

Results:

Acceptable recordings were obtained for every home T2PSG. When T1PSG and T2PSG were simultaneous, correlation between the number of arousals, respiratory disturbance index and sleep stages was excellent. T2PSG at home demonstrated less stage 2 sleep, more rapid eye movement (REM) sleep and higher sleep efficiency. Comparison of home T2PSG to T1PSG for diagnosing OSA showed a false positive rate of 6.6% and false negative rate of 3% for those performed at home.

Conclusions:

T2PSG in the home is feasible with excellent concordance with T1PSG for the purposes of diagnosing OSA in children aged 5-18 years. Home T2PSG may be more representative of a ’normal’ night for children and could benefit those suspected of having OSA by reducing waiting times for laboratory PSG, improving access to PSG and possibly reducing costs of investigating and treating OSA.



中文翻译:

带有便携式监测设备的家用 2 型多导睡眠图与实验室内 1 型多导睡眠图诊断儿童阻塞性睡眠呼吸暂停的比较

学习目标:

将 2 型多导睡眠图 (T2PSG) 与诊断儿童阻塞性睡眠呼吸暂停 (OSA) 的金标准 1 型实验室内多导睡眠图 (T1PSG) 进行比较;验证疑似 OSA 儿童的家庭 T2PSG。

方法:

81 名疑似 OSA 参与者(6-18 岁)在睡眠实验室同时患有 T1PSG 和 T2PSG,47 名参与者(5-16 岁)在睡眠实验室患有 T1PSG 并在家中进行 T2PSG。睡眠科学家对 PSG 数据进行上演和评分,儿科睡眠医生分配了正常或 OSA 的诊断。使用卡方和 Fischer 对名义变量的精确检验、对连续变量的 t 检验和 Cohen 的 kappa 来比较参与者的人口统计学、PSG 变量和诊断以评估一致性。

结果:

每个家庭 T2PSG 都获得了可接受的录音。当T1PSG和T2PSG同时发生时,觉醒次数、呼吸障碍指数和睡眠阶段之间的相关性极好。在家中的 T2PSG 表现出较少的第 2 阶段睡眠、更多的快速眼动 (REM) 睡眠和更高的睡眠效率。将家庭 T2PSG 与 T1PSG 用于诊断 OSA 的比较显示,在家中进行的那些的假阳性率为 6.6%,假阴性率为 3%。

结论:

T2PSG 在家中是可行的,与 T1PSG 具有良好的一致性,可用于诊断 5-18 岁儿童的 OSA。家庭 T2PSG 可能更能代表儿童的“正常”夜晚,并且可以通过减少实验室 PSG 的等待时间、改善获得 PSG 的机会以及可能降低调查和治疗 OSA 的成本,使怀疑患有 OSA 的人受益。

更新日期:2021-07-30
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