当前位置: X-MOL 学术Pediatrics › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Community SARS-CoV-2 Surge and Within-School Transmission
Pediatrics ( IF 8 ) Pub Date : 2021-10-01 , DOI: 10.1542/peds.2021-052686
Kanecia O Zimmerman 1, 2, 3 , M Alan Brookhart 4 , Ibukunoluwa C Kalu 3 , Angelique E Boutzoukas 3 , Kathleen A McGann 3 , Michael J Smith 3 , Gabriela M Maradiaga Panayotti 3 , Sarah C Armstrong 2 , David J Weber 5 , Ganga S Moorthy 3 , Daniel K Benjamin ,
Affiliation  

OBJECTIVES

When the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic began, experts raised concerns about in-person instruction in the setting of high levels of community transmission. We describe secondary transmission of SARS-CoV-2 within North Carolina kindergarten through 12th-grade school districts during a winter surge to determine if mitigation strategies can hinder within-school transmission.

METHODS

From October 26, 2020, to February 28, 2021, 13 North Carolina school districts participating in The ABC Science Collaborative were open for in-person instruction, adhered to basic mitigation strategies, and tracked community- and school-acquired SARS-CoV-2 cases. Public health officials adjudicated each case. We combined these data with that from August 2020 to evaluate the effect of the SARS-CoV-2 winter surge on infection rates as well as weekly community- and school-acquired cases. We evaluated the number of secondary cases generated by each primary case as well as the role of athletic activities in school-acquired cases.

RESULTS

More than 100 000 students and staff from 13 school districts attended school in person; of these, 4969 community-acquired SARS-CoV-2 infections were documented by molecular testing. Through contact tracing, North Carolina local health department staff identified an additional 209 infections among >26 000 school close contacts (secondary attack rate <1%). Most within-school transmissions in high schools (75%) were linked to school-sponsored sports. School-acquired cases slightly increased during the surge; however, within-school transmission rates remained constant, from presurge to surge, with ~1 school-acquired case for every 20 primary cases.

CONCLUSIONS

With adherence to basic mitigation strategies, within-school transmission of SARS-CoV-2 can be interrupted, even during a surge of community infections.



中文翻译:

社区 SARS-CoV-2 激增和校内传播

目标

当严重急性呼吸系统综合症冠状病毒 2 (SARS-CoV-2) 大流行开始时,专家们对在社区传播水平高的情况下进行面对面指导表示担忧。我们描述了 SARS-CoV-2 在冬季激增期间在北卡罗来纳州幼儿园到 12 年级学区的二次传播,以确定缓解策略是否可以阻碍校内传播。

方法

从 2020 年 10 月 26 日到 2021 年 2 月 28 日,参与 ABC Science Collaborative 的 13 个北卡罗来纳州学区开放接受面对面指导,坚持基本的缓解策略,并跟踪社区和学校获得的 SARS-CoV-2个案。公共卫生官员对每个病例​​进行裁决。我们将这些数据与 2020 年 8 月以来的数据相结合,以评估 SARS-CoV-2 冬季激增对感染率以及每周社区和学校获得性病例的影响。我们评估了每个原发性病例产生的继发性病例的数量,以及体育活动在学校获得性病例中的作用。

结果

来自13个学区的10万余名师生到校上学;其中,分子检测记录了 4969 例社区获得性 SARS-CoV-2 感染。通过接触者追踪,北卡罗来纳州当地卫生部门的工作人员在超过 26 000 名学校密切接触者中发现了另外 209 名感染者(二次发病率 <1%)。大多数高中校内传播 (75%) 与学校赞助的运动有关。激增期间学校获得性病例略有增加;然而,校内传播率从预激到激增保持不变,每 20 个初级病例就有约 1 个学校获得性病例。

结论

通过坚持基本的缓解策略,即使在社区感染激增期间,也可以阻断 SARS-CoV-2 的校内传播。

更新日期:2021-10-01
down
wechat
bug