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Insecticide-treated net ownership, utilization and knowledge of malaria in children residing in Batoke–Limbe, Mount Cameroon area: effect on malariometric and haematological indices
Malaria Journal ( IF 3 ) Pub Date : 2021-07-29 , DOI: 10.1186/s12936-021-03860-6
Rene Ning Teh 1, 2 , Irene Ule Ngole Sumbele 1, 3 , Derick Ndelle Meduke 1 , Gillian Asoba Nkeudem 1, 2 , Samuel Takang Ojong 1, 4 , Exodus Akwa Teh 5 , Helen Kuokuo Kimbi 1, 6
Affiliation  

Insecticide-treated nets (ITNs) are the most widely used interventions for malaria control in Africa. The aim of this study was to assess the ownership and utilization of ITNs and the knowledge of malaria and their effects on malariometric and haematological indices in children living in the Mount Cameroon area. A community-based cross-sectional study involving a total of 405 children aged between 6 months and 14 years living in Batoke–Limbe was carried out between July and October 2017. A semi-structured questionnaire was used to document demographic status, knowledge on malaria and ITN ownership and usage. Venous blood sample was collected from each child to determine the prevalence and intensity of parasitaemia by Giemsa-stained microscopy and full blood count by auto haematology analysis to obtain white blood cell (WBC) and red blood cell (RBC) counts, haemoglobin (Hb) level, haematocrit (Hct), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC). A multilinear regression model was used to determine the relationship between haematological parameter as dependent variable and the independent variables. The overall prevalence of parasitaemia, anaemia, knowledge about malaria, ITN ownership, usage and effective usage was 46.7%, 54.7%, 40.7%, 78.8%, 50.9% and 29.9%, respectively. The prevalence of parasitaemia was significantly higher (P < 0.001) in children who ineffectively utilized ITNs (54.9%) than effective users (27.3%). Having knowledge of malaria, negatively correlated with WBC counts (P = 0.005), but positively correlated with Hb levels (P < 0.001), RBC counts (P < 0.001), Hct (P < 0.001), MCV (P < 0.001) and MCH (P < 0.001). ITN use positively correlated with WBC counts (P = 0.005) but negatively with Hb levels (P = 0.004), RBC counts (P = 0.006), and MCH (P < 0.001). Meanwhile, parasitaemia negatively correlated with Hb levels (P = 0.004), RBC counts (P = 0.01), Hct (P = 0.04) and MCHC (P = 0.015). There is need for more sensitization on the benefits of using the ITNs to meet up with the intended and expected impact of the free distribution of ITNs.

中文翻译:

喀麦隆山地区 Batoke-Limbe 儿童的经杀虫剂处理的蚊帐所有权、利用和疟疾知识:对疟疾测定和血液学指数的影响

驱虫蚊帐 (ITN) 是非洲疟疾控制中使用最广泛的干预措施。本研究的目的是评估 ITN 的所有权和使用情况以及疟疾知识及其对喀麦隆山地区儿童的疟疾计量和血液学指数的影响。2017 年 7 月至 10 月期间,对居住在 Batoke-Limbe 的 405 名年龄在 6 个月至 14 岁之间的儿童进行了一项基于社区的横断面研究。以及 ITN 的所有权和使用。从每个孩子身上收集静脉血样本,通过吉姆萨染色显微镜确定寄生虫血症的患病率和强度,并通过自动血液学分析全血计数以获得白细胞(WBC)和红细胞(RBC)计数,血红蛋白(Hb)水平、血细胞比容 (Hct)、平均红细胞体积 (MCV)、平均红细胞血红蛋白 (MCH) 和平均红细胞血红蛋白浓度 (MCHC)。使用多元线性回归模型确定作为因变量的血液学参数与自变量之间的关系。寄生虫血症、贫血、疟疾知识、ITN拥有、使用和有效使用的总体患病率分别为46.7%、54.7%、40.7%、78.8%、50.9%和29.9%。寄生虫血症的患病率显着升高(P < 0. 001) 在无效使用 ITN 的儿童 (54.9%) 中比有效用户 (27.3%)。了解疟疾,与 WBC 计数呈负相关 (P = 0.005),但与 Hb 水平 (P < 0.001)、RBC 计数 (P < 0.001)、Hct (P < 0.001)、MCV (P < 0.001) 和妇幼保健 (P < 0.001)。ITN 使用与 WBC 计数 (P = 0.005) 呈正相关,但与 Hb 水平 (P = 0.004)、RBC 计数 (P = 0.006) 和 MCH (P < 0.001) 呈负相关。同时,寄生虫血症与 Hb 水平 (P = 0.004)、RBC 计数 (P = 0.01)、Hct (P = 0.04) 和 MCHC (P = 0.015) 呈负相关。需要更多地了解使用 ITN 的好处,以满足免费分发 ITN 的预期和预期影响。与 WBC 计数呈负相关 (P = 0.005),但与 Hb 水平 (P < 0.001)、RBC 计数 (P < 0.001)、Hct (P < 0.001)、MCV (P < 0.001) 和 MCH (P < 0.001) 呈正相关)。ITN 使用与 WBC 计数 (P = 0.005) 呈正相关,但与 Hb 水平 (P = 0.004)、RBC 计数 (P = 0.006) 和 MCH (P < 0.001) 呈负相关。同时,寄生虫血症与 Hb 水平 (P = 0.004)、RBC 计数 (P = 0.01)、Hct (P = 0.04) 和 MCHC (P = 0.015) 呈负相关。需要更多地了解使用 ITN 的好处,以满足免费分发 ITN 的预期和预期影响。与 WBC 计数呈负相关 (P = 0.005),但与 Hb 水平 (P < 0.001)、RBC 计数 (P < 0.001)、Hct (P < 0.001)、MCV (P < 0.001) 和 MCH (P < 0.001) 呈正相关)。ITN 使用与 WBC 计数 (P = 0.005) 呈正相关,但与 Hb 水平 (P = 0.004)、RBC 计数 (P = 0.006) 和 MCH (P < 0.001) 呈负相关。同时,寄生虫血症与 Hb 水平 (P = 0.004)、RBC 计数 (P = 0.01)、Hct (P = 0.04) 和 MCHC (P = 0.015) 呈负相关。需要更多地了解使用 ITN 的好处,以满足免费分发 ITN 的预期和预期影响。005) 但与 Hb 水平 (P = 0.004)、RBC 计数 (P = 0.006) 和 MCH (P < 0.001) 呈负相关。同时,寄生虫血症与 Hb 水平 (P = 0.004)、RBC 计数 (P = 0.01)、Hct (P = 0.04) 和 MCHC (P = 0.015) 呈负相关。需要更多地了解使用 ITN 的好处,以满足免费分发 ITN 的预期和预期影响。005) 但与 Hb 水平 (P = 0.004)、RBC 计数 (P = 0.006) 和 MCH (P < 0.001) 呈负相关。同时,寄生虫血症与 Hb 水平 (P = 0.004)、RBC 计数 (P = 0.01)、Hct (P = 0.04) 和 MCHC (P = 0.015) 呈负相关。需要更多地了解使用 ITN 的好处,以满足免费分发 ITN 的预期和预期影响。
更新日期:2021-07-29
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