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Body Composition and Metabolic Improvement in Patients Followed Up by a Multidisciplinary Team for Obesity in China
Journal of Diabetes Research ( IF 4.3 ) Pub Date : 2021-07-29 , DOI: 10.1155/2021/8862217 Difei Lu 1 , Zhenfang Yuan 1 , Lihua Yang 2 , Yong Jiang 3 , Min Li 4 , Yuanzheng Wang 5 , Lulu Jing 2 , Rongli Wang 4 , Junqing Zhang 1 , Xiaohui Guo 1
Journal of Diabetes Research ( IF 4.3 ) Pub Date : 2021-07-29 , DOI: 10.1155/2021/8862217 Difei Lu 1 , Zhenfang Yuan 1 , Lihua Yang 2 , Yong Jiang 3 , Min Li 4 , Yuanzheng Wang 5 , Lulu Jing 2 , Rongli Wang 4 , Junqing Zhang 1 , Xiaohui Guo 1
Affiliation
Background. This study evaluated the effectiveness of the multidisciplinary team (including a specialist, a dietitian, a physical exercise trainer, a surgeon for bariatric surgery, an acupuncturist, and several health educators) for obesity management and the body composition change and improvements in metabolic biomarkers during a 2-year follow-up. Materials and Methods. A total of 119 patients participated in the multidisciplinary team for obesity. Patients were followed up at 3 months, 6 months, 1 year, 18 months, and 2 years after their first visit. Individuals were divided into the high-protein diet (HPD) and standard-protein diet (SPD) group according to their results on a diet questionnaire that they filled out during follow-up. Results. After 1.2 years, the mean body weight of the participants dropped from 89.7 kg to 80.9 kg (). The body adiposity index was reduced from 33.9 to 32.0 (), while the fat-free mass index from 17.0 to 15.2 (). Fasting glucose and HbA1c were also lower after treatment ( and 0.038 for FPG and HbA1c, respectively). Fasting insulin and HOMA-IR were reduced ( and <0.001 for fasting insulin and HOMA-IR, respectively). HDL-c increased along with weight loss (1.06 mmol/L vs. 1.19 mmol/L, ), and transaminase levels significantly dropped ( and 0.021 for ALT and AST, respectively). During treatment, mean protein intake was 29.9% in the HPD group and 19.5% in the SPD group (). Weight loss, reduction of visceral fat area, maintenance of lean body mass, body adiposity index, and fat-free mass index showed no statistical significance between the HPD and SPD groups, as well as glucose metabolic variables. Conclusions. A multidisciplinary team for obesity management could significantly reduce body weight and improve metabolic indicators, including HDL-c, transaminase, and insulin resistance. A high-protein diet does not produce better weight control or body composition compared with a standard calorie-restricted diet.
更新日期：2021-07-29
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