A preparation method of compound foam dressing with antibacterial effect is introduced in this paper. Garlic oil, a natural antibacterial agent was coated with β-CD to form the garlic oil/β-CD microcapsule (MC). Then the microcapsule was added to the spinning solution with polyvinyl alcohol (PVA) and chitosan (CS) and was spun onto foam dressing to prepare garlic oil/CS/PVA nanofiber/foam compound dressings. The addition of garlic oil/β-CD microcapsule endowed the compound foam dressing with good antibacterial properties. The results shown that with the increase of MC, the antibacterial activity of compound dressing was further increased. MC 1.6 displayed the best antibacterial ability against E. coli and S. aureus (67.28 and 69.15 %), respectively. The liquid absorption properties increased from 16.86% to 17.91 % and the moisture content increased from 3.26 % to 5.29 %, compared to that of foam dressings. The mechanical properties of garlic oil/CS/PVA nanofiber/foam compound dressings increased by 4.6 N mm⁻² compared with the foam compound dressings, and the elongation at break increased by about 11.3 %.

介绍了一种具有抗菌作用的复合泡沫敷料的制备方法。大蒜油是一种天然抗菌剂，用 β-CD 包被以形成大蒜油/β-CD 微胶囊 (MC)。然后将微胶囊加入聚乙烯醇（PVA）和壳聚糖（CS）的纺丝溶液中，纺丝到泡沫敷料上制备大蒜油/CS/PVA纳米纤维/泡沫复合敷料。大蒜油/β-CD微胶囊的加入使复合泡沫敷料具有良好的抗菌性能。结果表明，随着MC的增加，复合敷料的抗菌活性进一步增强。MC 1.6 对大肠杆菌和金黄色葡萄球菌的抗菌能力最好(67.28 和 69.15 %)，分别。与泡沫敷料相比，吸液性能从 16.86% 增加到 17.91%，水分含量从 3.26% 增加到 5.29%。大蒜油/CS/PVA纳米纤维/泡沫复合敷料的力学性能比泡沫复合敷料提高了4.6 N mm ^-2，断裂伸长率提高了约11.3%。