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A study of the radial and bending performance for poly (L-lactic acid) braided stents with innovative runners
Polymers for Advanced Technologies ( IF 3.4 ) Pub Date : 2021-07-29 , DOI: 10.1002/pat.5461
Gutian Zhao 1 , Bin Wang 1 , Muqing Liu 1 , Yuan Tian 1 , Gensheng Wu 2 , Yi Zhang 3 , Jie Cheng 1 , Zhonghua Ni 1
Affiliation  

Poly (L-lactic acid) (PLLA) braided stent is expected to treat the peripheral vascular and biliary obstructive diseases with its excellent biocompatibility and biodegradability. However, the application of PLLA is still restricted by insufficient mechanical performance. In this paper, a series of PLLA braided stents with runners in axial, circumferential and spiral directions were prepared, and the effects of the runners on the mechanical performance of PLLA braided stents were studied. Meanwhile, the relationship between radial supporting performance and bending performance was analyzed to evaluate the effects on mechanical performance of PLLA stents. According to the relationship, it is found that the runners in different directions have a great influence on the mechanical performance of the stents. Especially the runners in spiral direction can effectively improve the radial force and bending stiffness of the stents compared with the control group. This work provides some suggestions for the development and design of PLLA braided stents in the future.

中文翻译:

具有创新流道的聚(L-乳酸)编织支架的径向和弯曲性能研究

聚(L-乳酸)(PLLA)编织支架以其优异的生物相容性和生物降解性有望治疗外周血管和胆道阻塞性疾病。然而,PLLA的应用仍然受到机械性能不足的限制。本文制备了一系列具有轴向、圆周和螺旋方向流道的PLLA编织支架,并研究了流道对PLLA编织支架力学性能的影响。同时,通过分析径向支撑性能与弯曲性能之间的关系,评估对PLLA支架力学性能的影响。根据该关系发现,不同方向的流道对支架的力学性能有很大影响。特别是螺旋方向的流道与对照组相比,可以有效提高支架的径向力和弯曲刚度。该工作为今后PLLA编织支架的开发和设计提供了一些建议。
更新日期:2021-07-29
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