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Role of body temperature variations in bat immune response to viral infections
Journal of The Royal Society Interface ( IF 3.9 ) Pub Date : 2021-07-28 , DOI: 10.1098/rsif.2021.0211
Maria Rita Fumagalli 1, 2 , Stefano Zapperi 3, 4 , Caterina A M La Porta 1, 2
Affiliation  

The ability of bats to coexist with viruses without being harmed is an interesting issue that is still under investigation. Here we use a mathematical model to show that the pattern of body temperature variations observed in bats between day and night is responsible for their ability to keep viruses in check. From the dynamical systems point of view, our model displays an intriguing quasi-periodic behaviour that might be relevant in making the system robust by avoiding viral escape due to perturbations in the body temperature cycle.



中文翻译:

体温变化在蝙蝠对病毒感染的免疫反应中的作用

蝙蝠与病毒共存而不受到伤害的能力是一个仍在研究​​中的有趣问题。在这里,我们使用一个数学模型来表明,蝙蝠在白天和黑夜之间观察到的体温变化模式是它们控制病毒的能力的原因。从动力系统的角度来看,我们的模型显示了一种有趣的准周期性行为,这可能与通过避免由于体温循环中的扰动引起的病毒逃逸而使系统变得健壮有关。

更新日期:2021-07-28
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