A novel way was adopted to graft zinc oxide (ZnO) with urethane-modified dimethacrylate (UDMA) in order to utilize them as reinforcing agents in resin-based dental composites. Experimental novel composites were synthesized having UDMA-grafted and nongrafted ZnO, at a concentration of 0 wt.%, 5 wt.%, and 10 wt.%. The same concentrations of ZnO were also incorporated in Filtek Z250 XT (3 M ESPE, USA). The antibacterial behavior was evaluated against Streptococcus mutans by direct-contact test at one, three, and seven days of incubation. The compressive strength and Vickers microhardness were tested as per ISO 9917 and ISO/CD6507-1, respectively. For abrasive wear resistance, mass loss and roughness average after tooth-brushing cycles of 24,000 at custom-made tooth-brushing simulator were evaluated using noncontact profilometer. Data analysis was carried out using post hoc Tucky’s test and nonparametric Kruskal–Wallis test. Direct contact test revealed that the antibacterial potential of novel and commercial composites was increased with an increase in the concentration of grafted ZnO as compared with nongrafted, whereby the potential was the highest at day seven. There was a significant decrease in compressive strength and Vickers hardness of commercial composites on addition of grafted ZnO while there was no significant difference in the strength of experimental novel composite. The abrasive wear of commercial and experimental composites was within clinical limits. Low-temperature flow-synthesis method was successfully employed to synthesize grafted and nongrafted ZnO. The UDMA-grafted ZnO can be incorporated into dental composites without decreasing their strength and these composites can be used to combat secondary caries.

采用一种新的方法将氧化锌（ZnO）与氨基甲酸酯改性二甲基丙烯酸酯（UDMA）接枝，以将其用作树脂基牙科复合材料的增强剂。合成了具有 UDMA 接枝和非接枝 ZnO 的实验性新型复合材料，浓度分别为 0 wt.%、5 wt.% 和 10 wt.%。在 Filtek Z250 XT（3 M ESPE，美国）中也加入了相同浓度的 ZnO。对变形链球菌的抗菌行为进行了评估在孵化的第 1 天、第 3 天和第 7 天通过直接接触测试。抗压强度和维氏显微硬度分别按照 ISO 9917 和 ISO/CD6507-1 进行测试。使用非接触式轮廓仪评估了在定制的刷牙模拟器上刷牙循环 24,000 次后的耐磨性、质量损失和平均粗糙度。使用事后Tucky's 检验和非参数Kruskal-Wallis 检验进行数据分析。直接接触测试表明，与未接枝相比，新型和商业复合材料的抗菌潜力随着接枝 ZnO 浓度的增加而增加，其中潜力在第 7 天最高。添加接枝 ZnO 后商业复合材料的抗压强度和维氏硬度显着降低，而实验新型复合材料的强度没有显着差异。商业和实验复合材料的磨料磨损在临床限制范围内。采用低温流动合成法成功合成了接枝和非接枝氧化锌。UDMA 接枝的 ZnO 可以掺入牙科复合材料中而不会降低其强度，这些复合材料可用于对抗继发性龋齿。