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CDX-1/CDX-2 Expression Is a Favorable Prognostic Factor in Epstein-Barr Virus-Negative, Mismatch Repair-Proficient Advanced Gastric Cancers.
Gut and Liver ( IF 3.4 ) Pub Date : 2021-07-28 , DOI: 10.5009/gnl20203
Kyeongmin Kim 1 , Songmi Noh 2 , Jae-Ho Cheong 3 , Hyunki Kim 1
Affiliation  

Caudal type homeobox (CDX)-1 and -2 are reportedly involved in the development and progression of gastric cancer (GC). Although there are several reports on the prognostic significance of CDX-2 expression in GC, it remains controversial. In this study, we sought to validate the prognostic value of CDX-1 and -2 expression according to the histologic and molecular subtypes of GC.

中文翻译:

CDX-1/CDX-2 表达是 Epstein-Barr 病毒阴性、错配修复熟练的晚期胃癌的有利预后因素。

据报道,尾端型同源盒 (CDX)-1 和 -2 与胃癌 (GC) 的发生和进展有关。尽管有一些关于 CDX-2 表达在 GC 中的预后意义的报告,但它仍然存在争议。在这项研究中,我们试图根据 GC 的组织学和分子亚型来验证 CDX-1 和 -2 表达的预后价值。
更新日期:2021-07-28
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