Perilipins are conserved proteins that decorate intracellular lipid droplets and are essential for lipid metabolism. To date, there is limited knowledge on their expression in human brain or their involvement in brain aging and neurodegeneration. The aim of this study was to characterise the expression levels of perilipins (Plin1–Plin5) in different cerebral areas from subjects of different age, with or without signs of neurodegeneration.

中文翻译：

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衰老和阿尔茨海默病期间人脑中周脂素的表达模式

Perilipins 是修饰细胞内脂滴的保守蛋白质，对脂质代谢至关重要。迄今为止，关于它们在人脑中的表达或它们参与大脑衰老和神经退行性变的知识有限。本研究的目的是表征来自不同年龄受试者的不同大脑区域中perilipins（Plin1-Plin5）的表达水平，有或没有神经退行性变的迹象。