Background. Mental problems can negatively impact physical and psychological well-being of junior medical students and predispose them to many unhealthy behaviors. Objective. We aimed to determine the prevalence and severity of depression, anxiety, and stress among medical undergraduate students of Arsi University and their association with substance use. Methods. Institutional-based cross-sectional study was conducted on 265 sampled medical students. Participants were selected by systematic random sampling. Data were collected by a pretested self-administrative questionnaire and analyzed using SPSS-21 software. Logistic regression analysis was employed, and statistical significance was accepted at . Result. In the present study, 5 questionnaires were rejected for incompleteness giving response rate of 98.1%. The mean age was 22.03 (SD = 2.074) years. The current prevalence rates of depression, anxiety, and stress were 52.3%, 60.8%, and 40.4%, respectively. The overall prevalence of khat chewing, cigarette smoking, and alcohol drinking was found to be 21.5%, 15.4%, and 33.8%, respectively. Depression was significantly associated with monthly income [AOR = 2.13], residency [AOR = 13.10], and alcohol drinking [AOR = 1.68]. Anxiety was associated with gender [AOR = 0.51], marital status [AOR = 0.46], educational year [AOR = 20.43], residency [AOR = 58.72], and cigarette smoking [AOR = 2.60]. Stress was significantly associated with monthly income [AOR = 2.21], educational year [AOR = 3.05], residency [AOR = 4.82], khat chewing [AOR = 1.90], and drinking alcohol [AOR = 1.84]. Conclusion. To sum up, depression, anxiety, and stress are common problems among medical students of Arsi University. Monthly income, residency, and alcohol drinking were identified as risk factors of both depression and stress. In addition to other mentioned factors, educational year and khat chewing were identified as risk factors of stress. However, gender, marital status, educational year, residency, and cigarette smoking were identified as risk factors of anxiety. Counselling and awareness creation are recommended.

中文翻译：

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埃塞俄比亚东南部 Arsi 大学医学本科生抑郁、焦虑和压力的患病率和严重程度及其与物质使用的关联

背景。心理问题会对初中医学生的身心健康产生负面影响，并使他们容易出现许多不健康的行为。目标。我们旨在确定 Arsi 大学医学本科生中抑郁、焦虑和压力的患病率和严重程度，以及它们与物质使用的关系。方法。对 265 名抽样医学生进行了基于机构的横断面研究。参与者是通过系统随机抽样选择的。通过预先测试的自我管理问卷收集数据，并使用 SPSS-21 软件进行分析。采用Logistic回归分析，统计显着性为. 结果. 在本研究中，5 份问卷因不完整而被拒绝，回复率为 98.1%。平均年龄为 22.03 (SD = 2.074) 岁。目前抑郁、焦虑和压力的患病率分别为 52.3%、60.8% 和 40.4%。咀嚼阿拉伯茶、吸烟和饮酒的总体流行率分别为 21.5%、15.4% 和 33.8%。抑郁症与月收入 [AOR = 2.13]、居住地 [AOR = 13.10] 和饮酒 [AOR = 1.68] 显着相关。焦虑与性别 [AOR = 0.51]、婚姻状况 [AOR = 0.46]、教育年限 [AOR = 20.43]、居住地 [AOR = 58.72] 和吸烟 [AOR = 2.60] 相关。压力与月收入 [AOR = 2.21]、学年 [AOR = 3.05]、居住地 [AOR = 4.82]、咀嚼阿拉伯茶 [AOR = 1.90]、结论。综上所述，抑郁、焦虑、压力是阿尔西大学医学生普遍存在的问题。月收入、居住地和饮酒被确定为抑郁和压力的危险因素。除了其他提到的因素外，教育年份和咀嚼阿拉伯茶被确定为压力的危险因素。然而，性别、婚姻状况、教育年限、居住地和吸烟被确定为焦虑的危险因素。建议进行咨询和提高认识。