Objective To investigate the relationships between diabetes-specific family conflict and health outcomes of young people with type 1 diabetes (T1D). Methods A systematic review was performed according to the PRISMA statement (registration number: CRD42020164988). PubMed, Embase, PsycNET, reference lists of included studies, and other relevant reviews were searched (1990–2020). Two independent reviewers screened titles, abstracts, and full-texts. Studies were included if they sampled young people with T1D (mean age between 14 and 25 years) and examined the relationship between diabetes-specific family conflict and the following outcomes: glycated hemoglobin (HbA1c), treatment adherence, blood glucose monitoring, depression, anxiety, quality of life, and/or well-being. Results A total of 20 studies met the predetermined inclusion criteria. Greater diabetes-specific family conflict was significantly related to higher HbA1c values in 17 studies. Seven studies reported a significant association between greater diabetes family conflict and suboptimal treatment adherence and/or less frequent blood glucose monitoring. However, significant relationships between conflict and HbA1c and/or treatment adherence were not found in four studies. Seven studies in total reported that greater diabetes family conflict was significantly related to poorer quality of life or well-being and greater depressive and/or anxiety symptoms in young people. Conclusions Diabetes-specific family conflict is associated with some adverse health outcomes for young people with T1D. However, more longitudinal studies of young people aged older than 16 years are needed. Screening for and addressing diabetes-specific family conflict is recommended, given the growing number of studies linking family conflict to various adverse health outcomes in young people with T1D.

中文翻译：

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系统评价：1 型糖尿病年轻人的糖尿病家庭冲突

目的探讨糖尿病特异性家庭冲突与青年1型糖尿病（T1D）健康结局的关系。方法根据PRISMA声明（注册号：CRD42020164988）进行系统评价。检索了 PubMed、Embase、PsycNET、纳入研究的参考文献列表和其他相关评论（1990-2020 年）。两名独立审稿人对标题、摘要和全文进行了筛选。如果他们对患有 T1D 的年轻人（平均年龄在 14 至 25 岁之间）进行抽样并检查糖尿病特异性家庭冲突与以下结果之间的关系，则纳入研究：糖化血红蛋白 (HbA1c)、治疗依从性、血糖监测、抑郁、焦虑、生活质量和/或幸福感。结果 共有 20 项研究符合预定的纳入标准。在 17 项研究中，更大的糖尿病特异性家庭冲突与更高的 HbA1c 值显着相关。七项研究报告了更大的糖尿病家庭冲突与次优治疗依从性和/或血糖监测频率降低之间存在显着关联。然而，在四项研究中未发现冲突与 HbA1c 和/或治疗依从性之间的显着关系。总共有七项研究报告说，更大的糖尿病家庭冲突与更差的生活质量或幸福感以及更严重的年轻人抑郁和/或焦虑症状显着相关。结论 糖尿病特有的家庭冲突与青少年 1 型糖尿病患者的一些不良健康结果相关。然而，需要对 16 岁以上的年轻人进行更多纵向研究。