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Management of ocular surface squamous neoplasia: Bowman Club Lecture 2021
BMJ Open Ophthalmology Pub Date : 2021-07-01 , DOI: 10.1136/bmjophth-2021-000842
Osmel Peter Alvarez 1 , Mike Zein 1 , Anat Galor 1, 2 , Carol L Karp 1
Affiliation  

The gold-standard treatment for ocular surface squamous neoplasia (OSSN) has traditionally been surgical excision with wide margins and a no-touch technique. However, surgery may be associated with several unfavourable sequelae, as well as significant recurrence rates if margins are positive. In recent years, topical chemotherapy with 5-fluorouracil, interferon α−2b and mitomycin C have emerged as valuable agents capable of effectively treating OSSN with varying adverse effects. These medical treatment options usually present additional costs to the patient but can allow patients to avoid surgery with fewer long-term effects. Anterior segment high-resolution optical coherence tomography is an excellent tool for diagnosing and monitoring OSSN and can be a useful aid for both surgical and medical treatments of OSSN. No data are available. Not applicable.

中文翻译:

眼表鳞状细胞瘤的管理:Bowman Club Lecture 2021

眼表鳞状细胞瘤 (OSSN) 的金标准治疗传统上是大边缘手术切除和非接触技术。然而,如果切缘阳性,手术可能会带来一些不利的后遗症,以及显着的复发率。近年来,5-氟尿嘧啶、干扰素 α-2b 和丝裂霉素 C 的局部化疗已成为能够有效治疗具有不同副作用的 OSSN 的有价值的药物。这些医疗选择通常会给患者带来额外的费用,但可以让患者避免手术,长期影响较小。前节高分辨率光学相干断层扫描是诊断和监测 OSSN 的绝佳工具,可以帮助 OSSN 的外科和药物治疗。没有可用数据。
更新日期:2021-07-27
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