Obesity prevalence is increasing worldwide, with significant healthcare implications. We searched PubMed/MEDLINE, Embase and the Cochrane Library for articles registered until June 2020 to explore the relationship between obesity and urinary (UI) and anal incontinence (AI). Obesity is associated with low-grade, systemic inflammation and proinflammatory cytokine release, producing reactive oxygen species and oxidative stress. This alters collagen metabolism and, in combination with increased intra-abdominal pressure, contributes to the development of UI. Whereas in AI, stool consistency may be a factor. Weight loss can reduce UI and should be a management focus; however, the effect of weight loss on AI is less clear.

中文翻译：

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肥胖对女性尿失禁和肛门失禁的作用：综述

肥胖患病率在全球范围内不断增加，对医疗保健产生重大影响。我们在 PubMed/MEDLINE、Embase 和 Cochrane 图书馆中搜索了截至 2020 年 6 月注册的文章，以探索肥胖与尿 (UI) 和肛门失禁 (AI) 之间的关系。肥胖与低度、全身炎症和促炎细胞因子释放有关，产生活性氧和氧化应激。这会改变胶原蛋白的代谢，并与增加的腹内压相结合，有助于 UI 的发展。而在 AI 中，粪便稠度可能是一个因素。减肥可以减少UI，应该是管理重点；然而，减肥对人工智能的影响还不太清楚。