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Expect the Unexpected—First Case of Congenital Rubella Syndrome in Israel in 20 Years: A Case Report
Journal of the Pediatric Infectious Diseases Society ( IF 3.2 ) Pub Date : 2021-07-26 , DOI: 10.1093/jpids/piab030
Michal Molad 1, 2 , Ayala Gover 1, 2 , Moshe Ephros 2, 3 , Karen Lavie-Nevo 1, 2 , Dan Waisman 1, 2 , Tal Levin 4 , Yara Kanaaneh 4 , Victoria Indenbaum 4
Affiliation  

Congenital rubella syndrome (CRS) is a devastating condition associated with significant morbidity. Due to universal vaccination programs, it is currently a rare condition, especially in developed countries. We report an infant born in Israel to a foreign worker from the Philippines who presented with a blueberry muffin rash immediately after birth. Initial workup revealed sonographic brain anomalies, abnormal hearing tests, and a patent ductus arteriosus. CRS was subsequently confirmed by laboratory diagnosis. Rubella virus genotype 1E was detected in the infant’s nasopharyngeal swab and urine samples. This was the first case of CRS in Israel in 20 years, emphasizing the need to “think outside the box” when dealing with infants of mothers who are foreign workers, refugees, or visitors of foreign relatives, in which rubella immune status is unknown. Additionally, public health authorities should consider the routine assessment of rubella immunity status of foreign workers in order to avoid such tragic, preventable diseases.

中文翻译:

期待意外——以色列 20 年来首例先天性风疹综合征:病例报告

先天性风疹综合征 (CRS) 是一种具有显着发病率的破坏性疾病。由于普遍的疫苗接种计划,它目前是一种罕见的疾病,尤其是在发达国家。我们将一名在以色列出生的婴儿报告给一名来自菲律宾的外国工人,他在出生后立即出现蓝莓松饼皮疹。初步检查显示脑部超声检查异常、听力测试异常和动脉导管未闭。随后通过实验室诊断证实了 CRS。在婴儿的鼻咽拭子和尿液样本中检测到风疹病毒基因型 1E。这是以色列 20 年来的首例 CRS,强调在处理外籍工人、难民或外国亲戚的访客的母亲的婴儿时需要“跳出框框思考”,其中风疹免疫状态未知。此外,公共卫生当局应考虑对外国工人的风疹免疫状况进行常规评估,以避免此类可预防的悲剧性疾病。
更新日期:2021-07-26
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