Examine the effect of subconcussive impact accumulation on cognitive/functional, imaging, and biomarker outcomes over the course of a single season, specifically in contact sport athletes at collegiate level or younger. Systematic review following PRISMA guidelines and using Oxford Center for Evidence-Based Medicine 2011 Levels of Evidence and Newcastle Ottawa Assessment Scale. PubMed MEDLINE, PsycInfo, SPORT-Discus, Web of Science. Original research in English that addressed the influence of subconcussive impacts on outcomes of interest with minimum preseason and postseason measurement in current youth, high school, or college-aged contact sport athletes. 796 articles were initially identified, and 48 articles were included in this review. The studies mostly involved male football athletes in high school or college and demonstrated an underrepresentation of female and youth studies. Additionally, operationalization of previous concussion history and concussion among studies was very inconsistent. Major methodological differences existed across studies, with ImPACT and diffusion tensor imaging being the most commonly used modalities. Biomarker studies generally showed negative effects, cognitive/functional studies mostly revealed no effects, and advanced imaging studies showed generally negative findings over the season; however, there was variability in the findings across all types of studies. This systematic review revealed growing literature on this topic, but inconsistent methodology and operationalization across studies makes it challenging to draw concrete conclusions. Overall, cognitive measures alone do not seem to detect changes across this timeframe while imaging and biomarker measures may be more sensitive to changes following subconcussive impacts.

检查亚震荡影响累积对单个赛季的认知/功能、成像和生物标志物结果的影响，特别是在大学水平或更年轻的接触运动运动员中。遵循 PRISMA 指南并使用牛津循证医学中心 2011 年证据水平和纽卡斯尔渥太华评估量表进行系统审查。PubMed MEDLINE、PsycInfo、SPORT-Discus、Web of Science。英文原创研究解决了对当前青年、高中或大学年龄接触性运动运动员的季前赛和季后赛最小测量结果的次震荡影响对感兴趣结果的影响。初步确定796篇文章，本次综述纳入48篇。这些研究主要涉及高中或大学的男性足球运动员，并表明女性和青年研究的代表性不足。此外，先前脑震荡史和研究中脑震荡的操作化非常不一致。研究之间存在主要的方法学差异，ImPACT 和扩散张量成像是最常用的方式。生物标志物研究通常显示负面影响，认知/功能研究大多显示没有影响，高级成像研究显示整个季节普遍存在负面发现；然而，所有类型的研究的结果都存在差异。该系统评价揭示了关于该主题的文献越来越多，但研究之间不一致的方法和可操作性使得得出具体结论具有挑战性。