Patient-reported outcome measures (PROMs) are used widely to elicit patient's self-appraisal of their health status and quality of life. One fundamental assumption when measuring PROMs is that all individuals interpret questions about their health status in a consistent manner. However, subgroups of patients with a similar health condition may respond differently to PROM questions (ie, differential item functioning [DIF]), leading to biased estimates of group differences on PROM scores. Understanding these differences can help inform the clinical interpretation of PROMs. This study examined whether DIF affects 10-item Quality of Life in Epilepsy (QOLIE10) scores reported by patients with epilepsy in outpatient clinics.

中文翻译：

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癫痫患者的生活质量：相同的问题，但对不同人的意义不同

患者报告的结果测量 (PROM) 被广泛用于引发患者对其健康状况和生活质量的自我评价。测量 PROM 时的一个基本假设是，所有个人都以一致的方式解释有关其健康状况的问题。然而，具有相似健康状况的患者亚组对 PROM 问题的反应可能不同（即差异项目功能 [DIF]），导致对 PROM 分数的组差异估计有偏差。了解这些差异有助于为 PROM 的临床解释提供信息。本研究检查 DIF 是否影响门诊癫痫患者报告的 10 项癫痫生活质量 (QOLIE10) 评分。