Re-planning for four-dimensional computed tomography (4DCT)-based lung adaptive radiotherapy commonly requires deformable dose mapping between the planning average-intensity image (AVG) and the newly acquired AVG. However, such AVG-AVG deformable image registration (DIR) lacks accuracy assessment. The current work quantified and compared geometric accuracies of AVG-AVG DIR and corresponding phase-phase DIRs, and subsequently investigated the clinical impact of such AVG-AVG DIR on deformable dose mapping.

中文翻译：

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基于 4DCT 的非小细胞肺癌自适应放疗平均强度图像之间可变形图像配准的几何和剂量精度

基于四维计算机断层扫描 (4DCT) 的肺自适应放疗的重新规划通常需要规划平均强度图像 (​​AVG) 和新采集的 AVG 之间的可变形剂量映射。然而，这种AVG-AVG变形图像配准（DIR）缺乏准确性评估。目前的工作量化并比较了AVG-AVG DIR和相应的相位DIR的几何精度，并随后研究了这种AVG-AVG DIR对可变形剂量图的临床影响。