This study provides insights into the spatial relationships among logistics agglomeration, technological progress, and air pollution in the sub-regions. From the perspective of new economic geography, the positive environmental externality of logistics agglomeration should outstrip its negative externality as the result of technological spillover. However, significant impacts of technological progress on the environment have not been identified in the logistics agglomeration sub-regions of many developing countries currently grappling with various environmental problems. This paper applies spatial econometrics and extended STIRPAT model to explore the roles the logistics agglomeration (LA) and technological progress (T) play in air pollution (I) using panel data from sub-regions of Chongqing in China between 2009 and 2019. The main conclusions are as follows. (1) In a global context, logistics agglomeration is a meaningful way to reduce air pollution under the interaction effect of technological progress. (2) In a sub-regional context: first, the suppressive effect of logistics agglomeration on air pollution gradually rebounds with the increase in agglomeration degree; secondly, the rebound effect of technological innovation is also evident in air pollution, and the rebound area gradually spreads from the metropolitan area to the peripheral sub-regions; finally, the interaction effect of logistics agglomeration and technological progress has a noteworthy suppression effect on air pollution, especially after the occurrence of the rebound effect of the logistics agglomeration and technological progress. In this regard, local governments should suppress the negative externalities of agglomeration with the interaction effects of technological progress while strengthening logistics agglomeration.