Abstract

In this study, it was focused on the synthesis of MgO nanoparticles by using dried jujube fruit extract through nontoxic and eco-friendly green method for the first time. The nanoparticles thereby obtained were characterized by UV–Vis spectroscopy, Fourier transform infrared spectroscopy, X-ray diffraction (XRD) analysis, scanning electron microscopy (SEM) in combination with energy-dispersive X-ray spectroscopy (EDX), and transmission electron microscopy (TEM). The formation of small-sized MgO nanoparticles was firstly confirmed by the maximum absorbance value at 320.3 nm. ATR-FTIR spectrums of the dried jujube fruit solid extract and G-MgO NPs showed the existence of bioactive compounds of the jujube fruit involving synthesis process of G-MgO NPs. According to the XRD analysis, the crystal structure of the nanoparticles was determined as face-centered cubic with the approximate average particle size of 21.96 nm. SEM-EDX and TEM analyses represented the synthesized MgO nanoparticles being durable and having spherical shape. We also found that while dried jujube fruit extract had no toxic effects, these nanoparticles show considerable effectiveness against eukaryotic model yeast Saccharomyces cerevisiae with the IC₅₀ value of 116.5 ppm.

摘要

本研究首次以无毒、环保的绿色方法利用枣干提取物合成MgO纳米粒子。由此获得的纳米颗粒通过紫外-可见光谱、傅里叶变换红外光谱、X射线衍射(XRD)分析、扫描电子显微镜(SEM)结合能量色散X射线光谱(EDX)和透射电子显微镜进行表征（透射电镜）。小尺寸 MgO 纳米颗粒的形成首先由 320.3 nm 处的最大吸光度值证实。干枣固体提取物和 G-MgO NPs 的 ATR-FTIR 光谱表明枣果中存在生物活性化合物，涉及 G-MgO NPs 的合成过程。根据XRD分析，纳米粒子的晶体结构被确定为面心立方，平均粒径约为 21.96 nm。SEM-EDX 和 TEM 分析表明合成的 MgO 纳米粒子具有耐用性和球形。我们还发现，虽然枣干提取物没有毒性作用，但这些纳米颗粒对真核模型酵母表现出相当大的有效性酿酒酵母的 IC ₅₀值为 116.5 ppm。