The influence of salinity on the effects of sodium lauryl sulfate (SLS) was evaluated using the Mediterranean mussel Mytilus galloprovincialis, exposed for 28 days to SLS (control-0.0 and 4.0 mg/L) under three salinity levels (Control-30, 25 and 35). The effects were monitored using biomarkers related to metabolism and energy reserves, defence mechanisms (antioxidant and biotransformation enzymes) and cellular damage. The results revealed that non-contaminated mussels tended to maintain their metabolic capacity regardless of salinity, without activation of antioxidant defence strategies. On the contrary, although contaminated mussels presented decreased metabolic capacity at salinities 25 and 35, they were able to activate their antioxidant mechanisms, preventing cellular damage. Overall, the present findings indicate that SLS, especially under stressful salinity levels, might potentially jeopardize population survival and reproduction success since reduced metabolism and alterations on mussels’ antioxidant mechanisms will impair their biochemical and, consequently, physiological performance.

使用地中海贻贝Mytilus galloprovincialis评估盐度对十二烷基硫酸钠 (SLS) 的影响, 在三个盐度水平 (Control-30, 25 和 35) 下暴露于 SLS (control-0.0 和 4.0 mg/L) 28 天。使用与代谢和能量储备、防御机制（抗氧化和生物转化酶）和细胞损伤相关的生物标志物监测效果。结果表明，无论盐度如何，未受污染的贻贝都倾向于保持其代谢能力，而无需激活抗氧化防御策略。相反，虽然受污染的贻贝在 25 和 35 盐度下的代谢能力下降，但它们能够激活其抗氧化机制，防止细胞损伤。总体而言，目前的研究结果表明，SLS，尤其是在压力盐度水平下，