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Interrelations of Cerebral Hemodynamics with Parameters of Cardiac Function and Brain Tissue in Patients with Ischemic Stroke
Bulletin of Experimental Biology and Medicine ( IF 0.7 ) Pub Date : 2021-07-23 , DOI: 10.1007/s10517-021-05219-y
A Yu Vishnyakova 1 , A B Berdalin 1 , A K Nikogosova 1 , I L Gubskiy 1 , D A Golovin 1 , V G Lelyuk 1
Affiliation  

We analyzed interrelations between the cerebral blood flow, cardiac output, and condition of the brain substance in 530 patients with ischemic stroke. Dependencies between the linear blood flow velocities in all arteries supplying the brain, as well as between the total volume blood flow through the internal carotid arteries and left ventricular stroke volume were revealed. The severity of atrophy was maximum in the parietal lobes (median 1.5 (1.0; 2.0)) and minimum in the occipital lobes (median 0.5 (0; 1.0)). Temporal lobes cortical atrophy significantly correlated with changes in the limbic system and in the periventricular and deep white matter; a significant weak inverse correlation of this parameter with blood flow in the middle cerebral artery was also found. Changes in the periventricular white matter (but not in deep white matter) demonstrated a significant inverse correlation with blood flow in the middle and anterior cerebral arteries.



中文翻译:

缺血性脑卒中患者脑血流动力学与心功能及脑组织参数的关系

我们分析了 530 例缺血性卒中患者的脑血流量、心输出量和脑物质状况之间的相互关系。揭示了供应大脑的所有动脉中的线性血流速度之间的依赖性,以及通过颈内动脉的总血流量与左心室每搏输出量之间的依赖性。萎缩的严重程度在顶叶最高(中位数 1.5(1.0;2.0)),在枕叶最低(中位数 0.5(0;1.0))。颞叶皮质萎缩与边缘系统、脑室周围和深部白质的变化显着相关;还发现该参数与大脑中动脉血流呈显着弱负相关。

更新日期:2021-07-23
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