The brain mechanisms underlying conditioned aversion learning in birds were studied using experimental model in young chicks. The learning consisted of a conditioning stimulus presentation followed by a delayed sickness-inducing treatment reinforcement. Intraventricular administration of an NMDA receptor antagonist MK-801, a protein synthesis inhibitor anisomycin, or an inhibitor of glycoprotein fucosylation 2-deoxygalactose just before presentation of the conditioning stimulus prevented aversion learning. Injections of the same chemicals before reinforcement did not affect learning. The obtained results show that the investigated mechanisms underlying aversion learning were critical at the early stage of memory formation. Later processes of association of the conditioning stimulus with the reinforcement appear to be independent of the NMDA receptors and protein synthesis/glycosylation, or alternatively to be located in other brain areas.

使用小鸡的实验模型研究了鸟类条件厌恶学习的大脑机制。学习包括条件刺激呈现，然后是延迟的诱发疾病的治疗强化。NMDA 受体拮抗剂 MK-801、蛋白质合成抑制剂茴香霉素或糖蛋白岩藻糖基化 2-脱氧半乳糖抑制剂的脑室内给药恰好在条件刺激出现之前阻止了厌恶学习。在强化之前注射相同的化学物质不会影响学习。获得的结果表明，厌恶学习的研究机制在记忆形成的早期阶段是至关重要的。