Transition metal-catalyzed asymmetric hydrofunctionalization of alkenes provides straightforward approaches to access optically active organic compounds. Rhodium compounds ligated by chiral phosphine ligands are the most frequently used catalysts for enantioselective hydrogenation reactions of unsaturated organic molecules containing C=C and C=N bonds. However, the rapid development of cobalt catalysis over the past decade shows that some cobalt catalysts have equal or even better catalytic performances compared with their rhodium congeners in asymmetric hydrofunctionalization reactions of alkenes. This review highlights recent progress in cobalt-catalyzed enantioselective hydrogenation and hydroboration of alkenes, mainly from 2018 to early 2021. Mechanistic considerations of these cobalt-catalyzed reactions will also be discussed.

过渡金属催化的烯烃不对称加氢官能化提供了获得光学活性有机化合物的直接方法。由手性膦配体连接的铑化合物是最常用于含有 C=C 和 C=N 键的不饱和有机分子的对映选择性氢化反应的催化剂。然而，过去十年钴催化的快速发展表明，在烯烃的不对称加氢官能化反应中，一些钴催化剂与其铑同类物相比具有同等甚至更好的催化性能。本综述重点介绍了 2018 年至 2021 年初钴催化的烯烃对映选择性氢化和硼氢化的最新进展。还将讨论这些钴催化反应的机理考虑。