Abstract

The studies for blood of bull sires have provided the opportunity to use the level of serum immunoglobulins of the G isotype as a biomarker to classify the animals according to stability and variability in the syntheses of antibodies. Based on the produced classification, the bulls’ progeny first-calf heifers were allocated into two groups. The objective of the survey is to study the innate immunity of first-calf heifers that are the progeny of bull sires having steady-state (group one) and unsteady-state (group two) IgG values. In autumn and spring, the blood was sampled from the animals in order to estimate the leucocyte count with the calculation formula and the concentrations of immunoglobulins of the G and M isotopes in blood serum with the single radial immunodiffusion method. Immunoreactivity of blood cells (shift index) was measured with the load test based on the phagocytic cell reaction with S. dublin metabolites. Thus, the shift index in autumn for groups one and two comprised 1.28 and 1.66, respectively. In spring, the functional potential of phagocytes sharply reduced; the index comprised 0.64 and 0.26, respectively. In autumn, the phagocytic activity was 1.8 times lower and the IgG and IgM concentrations were higher in the first-calf heifers produced from the bulls of group two than that in the daughters of the bulls having the steady-state parameter values (group one). The total serum IgG level in the bull sires having the steady-state parameter values correlates with the same parameters of their daughters (r = 0.53), which can serve as a positive factor to inherit this trait.

中文翻译：

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公牛公牛 IgG 水平与其女儿先天免疫参数之间的关联

摘要

对公牛血液的研究提供了使用 G 同种型血清免疫球蛋白水平作为生物标志物的机会，可以根据抗体合成的稳定性和可变性对动物进行分类。根据产生的分类，公牛的后代第一胎小母牛被分为两组。调查的目的是研究作为具有稳态（第一组）和非稳态（第二组）IgG 值的公牛后代的一头犊牛的先天免疫。秋、春季采血，用计算公式估算白细胞计数，用单放射免疫扩散法测血清中G、M同位素免疫球蛋白浓度。都柏林链球菌代谢物。因此，第一组和第二组的秋季班次指数分别为 1.28 和 1.66。春季，吞噬细胞的功能潜能急剧下降；该指数分别为 0.64 和 0.26。在秋季，与具有稳态参数值的公牛（第一组）公牛的子代相比，第二组公牛生产的头胎小母牛的吞噬活性低 1.8 倍，IgG 和 IgM 浓度高. 具有稳态参数值的公牛的总血清 IgG 水平与其子代的相同参数 ( r = 0.53) 相关，这可以作为遗传该特性的积极因素。