Currently, the mass culling of infected poultry as well as those that may have had contact with them is an essential part of prevention and disease control strategy, amidst the growing concerns over the avian influenza virus (AIV) spreading nationwide; however, it is largely dependent on effective biosecurity measures, including disinfection. Although many disinfectants are commercially available for veterinary use, information on the virucidal efficacy of individual active components in disinfectants is limited, since most disinfectants are complex formulations of active substances. This study aimed to evaluate the virucidal efficacy of individual active components in commercial disinfectants. Seven representative active substances in commercial disinfectants used against AIV in South Korea during the year 2020, namely potassium peroxymonosulfate (PPMS), sodium dichloroisocyanurate (NaDCC), malic acid (MA), citric acid (CA), glutaraldehyde (GLT), benzalkonium chloride (BZK), and didecyldimethylammonium chloride (DDAC), were tested to confirm their individual virucidal efficacy against H9N2 low pathogenic avian influenza virus. The specific selection of active substances and their test concentrations was done based on the formulation of 202 disinfectants approved by Animal and Plant Quarantine Agency as being effective against AIV. Minimal virucidal concentrations are as follows: for PPMS, 0.2%; for NaDCC, 0.1%; for MA, 0.5%; for CA, 0.4%; for GLT, 0.01%; for BZK, 0.4%; and for DDAC, 0.2%. The current study not only highlighted the virucidal efficacy of these active substances against AIV but also indicated its impact on the biosecurity measures, particularly for selection of a disinfectant and its proper application in poultry industry.

目前，在对禽流感病毒 ( AIV)日益关注的情况下，大规模扑杀受感染的家禽以及可能与其接触过的家禽是预防和疾病控制策略的重要组成部分。) 在全国范围内传播；然而，这在很大程度上取决于有效的生物安全措施，包括消毒。尽管许多消毒剂可用于兽医用途，但关于消毒剂中单个活性成分的杀病毒功效的信息是有限的，因为大多数消毒剂是活性物质的复杂配方。本研究旨在评估商业消毒剂中单个活性成分的杀病毒功效。2020年韩国抗AIV商用消毒剂中的七种代表性活性物质，即过硫酸钾（PPMS）、二氯异氰尿酸钠（NaDCC）、苹果酸（MA）、柠檬酸（CA）、戊二醛（GLT）)、苯扎氯铵 ( BZK ) 和二癸基二甲基氯化铵 ( DDAC)), 以确认它们对 H9N2 低致病性禽流感病毒的单独杀病毒功效。活性物质的具体选择及其试验浓度是根据动植物检疫局批准的对AIV有效的202种消毒剂的配方进行的。最低杀病毒浓度如下：对于 PPMS，0.2%；对于 NaDCC，0.1%；对于 MA，0.5%；对于 CA，0.4%；对于 GLT，0.01%；对于 BZK，0.4%；对于 DDAC，为 0.2%。目前的研究不仅强调了这些活性物质对 AIV 的杀病毒功效，而且还表明了其对生物安全措施的影响，特别是对消毒剂的选择及其在家禽业的正确应用。