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The role of cellular active stresses in shaping the zebrafish body axis
Current Opinion in Cell Biology ( IF 7.5 ) Pub Date : 2021-07-22 , DOI: 10.1016/j.ceb.2021.06.002
Rachna Narayanan 1 , Mario A Mendieta-Serrano 1 , Timothy E Saunders 2
Affiliation  

Tissue remodelling and organ shaping during morphogenesis are products of mechanical forces generated at the cellular level. These cell-scale forces can be coordinated across the tissue via information provided by biochemical and mechanical cues. Such coordination leads to the generation of complex tissue shape during morphogenesis. In this short review, we elaborate the role of cellular active stresses in vertebrate axis morphogenesis, primarily using examples from postgastrulation development of the zebrafish embryo.



中文翻译:

细胞活性应激在斑马鱼体轴形成中的作用

形态发生过程中的组织重塑和器官成形是细胞水平产生的机械力的产物。这些细胞规模的力量可以通过生化和机械线索提供的信息在整个组织中进行协调。这种协调导致在形态发生过程中产生复杂的组织形状。在这篇简短的回顾中,我们主要使用斑马鱼胚胎原肠胚发育后的例子来阐述细胞活跃应激在脊椎动物轴形态发生中的作用。

更新日期:2021-07-22
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