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Phytochemical evaluation and pharmacognostic standardization of Syzygium palghatense endemic to Western Ghats
Future Journal of Pharmaceutical Sciences Pub Date : 2021-07-22 , DOI: 10.1186/s43094-021-00282-8
V. R. Snehalatha 1 , A. R. Rasmi 1
Affiliation  

The plants belonging to the genus Syzygium has received much attention since ancient times due to its multidimensional uses for mankind. These plants in general, reported to contain a wide array of phytomolecules with a broad spectrum of biological activities that include antihypoglycemic, antioxidant, anti-inflammatory, anticarcinogenic, and antihypertensive properties. The pharmacological potential of S. palghatense which is endemic to Western Ghats has not yet been investigated. The present study was intended to examine the potential benefits of the leaves and bark of S. palghatense. Morpho-anatomical studies of S. palghatense provided useful details for the identification. The pharmacological characterization of the plants shows significant results in their studied parameters. The total phenolic and flavonoid contents were higher in methanolic extracts of leaves and bark of S. palghatense. Methanolic extract of the leaves and bark have superior antioxidant capacity when compared with the chloroform, ethyl acetate, and distilled water extracts. A significant result in alpha amylase and alpha glucosidase enzyme activity was exhibited when antidiabetic study was performed. The current study showed that the methanolic extract of S. palghatense leaves and bark have significant pharmacognostic properties and potential antioxidant and antidiabetic compounds. Phytochemical studies portray the presence of several biologically active secondary metabolites, including essential oil, alkaloid, glycosides, carbohydrate, tannins, reducing sugar, phenolics, and saponins, which may be the reason for its biological properties. As compared to bark, leaves of S. palghatense possess significant activity toward all the biological properties tested.

中文翻译:

西高止山脉特有的蒲甘草的植物化学评价和生药学标准化

丁香属植物自古以来就因其对人类的多维用途而备受关注。据报道,这些植物通常含有多种植物分子,具有广泛的生物活性,包括降血糖、抗氧化、抗炎、抗癌和抗高血压特性。尚未研究西高止山脉特有的 S. palghatense 的药理学潜力。本研究旨在检查 S. palghatense 的叶子和树皮的潜在益处。S. palghatense 的形态解剖学研究为鉴定提供了有用的细节。植物的药理学特征在其研究参数中显示出显着的结果。S. palghatense 叶子和树皮的甲醇提取物中的总酚类和类黄酮含量较高。与氯仿、乙酸乙酯和蒸馏水提取物相比,叶子和树皮的甲醇提取物具有更强的抗氧化能力。在进行抗糖尿病研究时,α 淀粉酶和 α 葡萄糖苷酶的酶活性表现出显着的结果。目前的研究表明,S. palghatense 叶和树皮的甲醇提取物具有显着的生药特性和潜在的抗氧化和抗糖尿病化合物。植物化学研究表明存在几种具有生物活性的次级代谢产物,包括精油、生物碱、糖苷、碳水化合物、单宁、还原糖、酚类和皂苷,这可能是其生物学特性的原因。
更新日期:2021-07-22
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