In 167 men with vibration syndrome (VS), allele and genotype frequencies of HSPA1B (+1267A>G) genetic polymorphism (rs1061581) were studied depending on the type of vibration exposure and on the presence or absence of metabolic syndrome (MetS). The examined subjects were divided into two groups: VS patients (n=80) and VS+MetS patients (n=87). The differences in the lipid profiles between groups were revealed against the background of the lack of distinctions in the age of patients for A/G and G/G genotypes carriers. An increase in A/A (p=0.03) and a decrease in A/G (p=0.04) genotype frequencies in VS patients caused by hand-transmitted vibration in comparison with those in whom the disease was caused by a combination of hand-transmitted and whole-body vibration were found. The shifts in the frequencies of the above genotypes (p=0.01) were similar in patients with both types of vibration exposure in the VS+MetS group in comparison with VS group; the carriage of genotypes with the G allele in VS group exceeded that in VS+MetS group (p=0.01).

在167名男性振动综合征（VS），等位基因频率和基因型频率HSPA1B（1267甲> G ^）的遗传多态性（rs1061581中研究了根据振动暴露的类型和代谢综合征（代谢综合征）的存在或不存在）。检查对象分为两组：VS患者（n =80）和VS+MetS患者（n =87）。在A / G和G / G基因型携带者的患者年龄缺乏差异的背景下，揭示了组间脂质谱的差异。A / A的增加( p = 0.03) 和A / G ( p = 0.04) 基因型频率在 VS 患者中由手传递振动引起的与那些由手传递和全身振动组合引起的疾病相比降低被找到。VS+MetS组与VS组相比，上述基因型的频率变化（p =0.01）相似；VS组G等位基因携带量超过VS+MetS组（p =0.01）。