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Bacterial lysate add-on therapy to reduce exacerbations in severe asthma: A double-blind placebo-controlled trial
Clinical & Experimental Allergy ( IF 6.1 ) Pub Date : 2021-07-21 , DOI: 10.1111/cea.13990
Geertje M de Boer 1, 2 , Gert-Jan Braunstahl 1, 2 , Esmee K van der Ploeg 2, 3 , Cathelijne M van Zelst 1, 2 , Alie van Bruggen 1 , Guido Epping 1 , Menno van Nimwegen 2 , Gert Verhoeven 4 , Erwin Birnie 5 , Bianca M Boxma-de Klerk 5 , Marjolein J W de Bruijn 2 , Ralph Stadhouders 2, 3 , Rudi W Hendriks 2 , Gerdien A Tramper-Stranders 2, 6
Affiliation  

Asthma exacerbations are frequently induced by respiratory tract infections (RTIs). Bacterial lysates have been described to possess immune-modulatory effects and reduce RTIs as well as asthma symptoms in children. However, whether bacterial lysates have similar effects in adult asthma patients is unknown.

中文翻译:

细菌裂解物附加疗法可减少严重哮喘的恶化:一项双盲安慰剂对照试验

呼吸道感染 (RTIs) 经常诱发哮喘发作。细菌裂解物已被描述为具有免疫调节作用并减少儿童的 RTI 和哮喘症状。然而,细菌裂解物是否对成人哮喘患者有类似的作用尚不清楚。
更新日期:2021-09-03
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