Mathematical modeling is a distinctive tool for improving yield and selection when extracting bioactive compounds from plant matrices. The objective of this study is to model the extraction of the main bioactive compounds from jackfruit seeds using supercritical CO₂ to reveal aspects of mass transfer associated to this process. Two extraction conditions (12 MPa/40 °C/3 mL min^-1 and 20 MPa/50 °C/4 mL min^-1), particles with two different radius (0.170 mm and 0.370 mm) and three compounds determined by GC/MS were evaluated (13,27-cycloursan-3-one, 9,19-cycloergost-24(28)-en-3-ol,4,14-dimethyl-,acetate,(3β,4α, 5α) and lanosterol). The model used employed differential mass balances to evaluate the flow of mass through the fluid-particle interface applying film resistance to the interface of the bulk with the fluid. The results indicate that higher solvent specific mass optimizes the extraction of the compounds of interest and that smaller particles facilitate the convection of extraction, accelerating the obtention of compounds at the beginning of the experiment.

从植物基质中提取生物活性化合物时，数学建模是提高产量和选择的独特工具。本研究的目的是模拟使用超临界 CO ₂从菠萝蜜种子中提取主要生物活性化合物的过程，以揭示与该过程相关的传质方面。两种萃取条件（12  MPa/40 °C/3  mL  min ^-1和 20  MPa/50 °C/4  mL  min ^-1），具有两种不同半径（0.170  mm 和 0.370 mm) 和 GC/MS 测定的三种化合物（13,27-环乌山-3-one, 9,19-环麦角-24(28)-en-3-ol,4,14-二甲基-,乙酸盐,( 3β、4α、5α) 和羊毛甾醇)。使用的模型采用微分质量平衡来评估通过流体 - 颗粒界面的质量流量，将薄膜阻力施加到主体与流体的界面。结果表明，较高的溶剂比质量优化了目标化合物的提取，较小的颗粒促进了提取的对流，在实验开始时加速了化合物的获得。