Implant prosthetics composed of the Ti6Al4V alloy are prone to releasing harmful metal ions into surrounding tissue, as well as causing bacterial infections, in the human body. In order to address these problems, the surface of the Ti6Al4V alloy was grafted with polydopamine (PDA) and then coated with a graphene oxide/zinc oxide (GO/ZnO) nanocomposite coating by both hydrothermal growth and drop-casting methods. The phase composition, microstructure, wettability, corrosion resistance, and antibacterial activities of the nanocomposite coatings at each stage of growth were systematically analyzed. The results showed that the ZnO/PDA nanocoating and GO/ZnO/PDA nanocomposite coating demonstrated excellent wettability properties as well as antibacterial activities against Escherichia coli and Staphylococcus aureus. The introduction of GO into the ZnO/PDA nanocoating enhanced the ability of the nanocoating, which synergistically enabled the mineralization of hydroxyapatite onto the nanocomposite coating while immersed in a simulated body fluid (SBF) solution. The GO/ZnO/PDA nanocomposite coating also improved the corrosion resistance of Ti6Al4V substrate in Ringer's solution by preventing the diffusion of corrosive electrolyte ions through the coating to the Ti6Al4V substrate.

由 Ti6Al4V 合金制成的种植体假肢容易将有害金属离子释放到周围组织中，并在人体中引起细菌感染。为了解决这些问题，Ti6Al4V 合金的表面接枝了聚多巴胺 (PDA)，然后通过水热生长和滴铸方法涂覆了氧化石墨烯/氧化锌 (GO/ZnO) 纳米复合涂层。系统地分析了纳米复合涂层在生长各个阶段的相组成、微观结构、润湿性、耐腐蚀性和抗菌活性。结果表明，ZnO/PDA纳米涂层和GO/ZnO/PDA纳米复合涂层表现出优异的润湿性以及对大肠杆菌和大肠杆菌的抗菌活性。金黄色葡萄球菌。将 GO 引入 ZnO/PDA 纳米涂层增强了纳米涂层的能力，这协同作用使羟基磷灰石在浸入模拟体液 (SBF) 溶液时矿化到纳米复合涂层上。GO/ZnO/PDA 纳米复合涂层还通过防止腐蚀性电解质离子通过涂层扩散到 Ti6Al4V 基体，提高了 Ti6Al4V 基体在林格溶液中的耐腐蚀性。