Clinical data of five patients with hepatic metastases of retinoblastoma were analyzed retrospectively (two had bilateral tumors three had unilateral intraocular tumors). On computed tomography, multiple and single low-density foci were observed. Four patients had tumor remission, and one showed no response after chemotherapy. Three patients who underwent enucleation were at high risk for extensive choroidal invasion. Central nervous system and bone metastases occurred in all five patients. Neuron-specific enolase and lactate dehydrogenase levels were significantly elevated in all patients. Two patients died (not from hepatic metastasis). Three patients (one with tumor progression and two with shorter courses) are continuing treatment.

中文翻译：

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视网膜母细胞瘤肝转移的临床特征及影像学表现

回顾性分析了5例视网膜母细胞瘤肝转移患者的临床资料（2例为双侧肿瘤，3例为单侧眼内肿瘤）。在计算机断层扫描中，观察到多个和单个低密度病灶。4 例患者肿瘤缓解，1 例化疗后无反应。三名接受眼球摘除术的患者存在广泛脉络膜浸润的高风险。所有五名患者均发生中枢神经系统和骨转移。所有患者的神经元特异性烯醇化酶和乳酸脱氢酶水平均显着升高。两名患者死亡（非肝转移）。三名患者（一名肿瘤进展，两名疗程较短）正在继续治疗。