Statins have plausible biological effects against prostate cancer cells and are associated with improved disease-specific mortality. In current randomized placebo-controlled trial, low-dose atorvastatin caused no difference in relapses after radical prostatectomy in Asian men. Future trials should study higher statin doses at later disease stages with survival as the endpoint. See related article by Jeong et al., [p. 5004][1] [1]: /lookup/volpage/27/5004?iss=18

中文翻译：

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前列腺癌的他汀类药物：何时服用以及服用多少？

他汀类药物对前列腺癌细胞具有合理的生物学作用，并与疾病特异性死亡率的提高有关。在目前的随机安慰剂对照试验中，低剂量阿托伐他汀对亚洲男性根治性前列腺切除术后的复发没有影响。未来的试验应以生存为终点，研究在疾病后期使用更高剂量的他汀类药物。参见 Jeong 等人的相关文章，[p. 5004][1][1]：/lookup/volpage/27/5004?iss=18