Offspring born to mothers with asthma in pregnancy are known to have lower lung function which tracks with age. Human group 2 innate lymphoid cells (ILC2) accumulate in foetal lungs, at 10-fold higher levels compared to adult lungs. However, there are no data on foetal ILC2 numbers and the association with respiratory health outcomes such as lung function in early life. We aimed to investigate cord blood immune cell populations from babies born to mothers with asthma in pregnancy.

中文翻译：

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脐带血 2 型先天性淋巴细胞与 6 周龄时的肺功能有关

众所周知，怀孕期间患有哮喘的母亲所生的后代肺功能随着年龄的增长而降低。人类第 2 组先天性淋巴细胞 (ILC2) 在胎儿肺部积聚，与成人肺部相比，其水平高出 10 倍。然而，没有关于胎儿 ILC2 数量以及与生命早期肺功能等呼吸健康结果相关性的数据。我们的目的是调查妊娠期患有哮喘的母亲所生婴儿的脐带血免疫细胞群。