The prevalence of congenital anomalies in newborns in South Korea was 272.9 per 100,000 in 2005, and 314.7 per 100,000 in 2006. In other studies, the prevalence of congenital anomalies in South Korea was equivalent to 286.9 per 10,000 livebirths in 2006, while it was estimated 446.3 per 10,000 births during the period from 2008 to 2014. Several systematic reviews and meta-analyses analyzing the factors contributing to congenital anomalies have been reported, but comprehensive umbrella reviews are lacking.

中文翻译：

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先天性异常的环境和遗传风险因素：系统评价和元分析的总括审查。

2005 年韩国新生儿先天畸形患病率为每 10 万人 272.9 例，2006 年为每 10 万人 314.7 例。在其他研究中，韩国的先天畸形患病率相当于每 10,000 例 286.9 例，而估计为 2006 例活产儿2008 年至 2014 年期间每 10,000 名新生儿中有 446.3 人。已经报告了几项分析导致先天性异常的因素的系统评价和荟萃分析，但缺乏全面的综合评价。