Cholecystitis is an important risk factor for gallbladder cancer, but the bile microbiome and its association with gallbladder disease has not been investigated fully. We aimed to analyze the bile microbiome in normal conditions, chronic cholecystitis, and gallbladder cancer, and to identify candidate bacteria that play an important role in gallbladder carcinogenesis.

中文翻译：

---

通过胆汁微生物组分析确定的微生物失调与胆囊疾病的关联。

胆囊炎是胆囊癌的重要危险因素，但胆汁微生物组及其与胆囊疾病的关系尚未得到充分研究。我们旨在分析正常情况下、慢性胆囊炎和胆囊癌中的胆汁微生物组，并确定在胆囊癌发生中起重要作用的候选细菌。