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Aortic homograft for aortic valve replacement in patient with Alpha-Gal allergy
General Thoracic and Cardiovascular Surgery ( IF 1.2 ) Pub Date : 2021-07-19 , DOI: 10.1007/s11748-021-01684-4
Simon Dang Van 1 , Olivier Fouquet 1, 2 , Audrey Jeanneteau 3 , Jean-Marie Leclere 4 , Christophe Baufreton 1, 2
Affiliation  

Allergy to Galactose-Alpha-1,3-Galactose is an allergy to mammalian proteins, that are present on the surface of standard bioprosthestic valves, and could result in a catastrophic allergic reaction or may cause early deterioration of the bioprostheses. Aortic homograft is an acceptable alternative to standard prosthetic valves (biological and mechanical) to avoid a potential allergic manifestation and the need for definitive oral anticoagulation. We report the implantation of an aortic homograft in a patient with an aortic stenosis who presents a documented AlphaGal allergy.



中文翻译:

主动脉同种移植物用于 Alpha-Gal 过敏患者的主动脉瓣置换术

对半乳糖-α-1,3-半乳糖过敏是对存在于标准生物假体瓣膜表面的哺乳动物蛋白质过敏,可能导致灾难性的过敏反应或可能导致生物假体过早退化。主动脉同种移植是标准人工瓣膜(生物和机械)的可接受替代方案,以避免潜在的过敏表现和最终口服抗凝剂的需要。我们报告了在主动脉瓣狭窄患者中植入主动脉同种移植物,该患者有记录的 AlphaGal 过敏。

更新日期:2021-07-19
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