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Crocin Promotes Apoptosis in Human EBV-Transformed B-Lymphocyte via Intrinsic Pathway.
Mediterranean Journal of Hematology and Infectious Diseases ( IF 3.2 ) Pub Date : 2021-07-01 , DOI: 10.4084/mjhid.2021.049
Abdolreza Sotoodeh Jahromi 1 , Mohammad Kargar 1 , Farshid Kafilzadeh 1 , Marzieh Jamalidoust 2 , Maliheh Moradzadeh 3
Affiliation  

As a major carotenoid in saffron, crocin demonstrates potent anti-cancer impacts. However, its anti-lymphoma effects remain vague, especially in the human EBV-associated B-cell lymphoproliferative disorders. This study examined crocin's apoptogenic potential and its underlying mechanism in CO 88BV59-1 cell line vs. normal human peripheral blood B cells.

中文翻译:

Crocin 通过内在途径促进人 EBV 转化的 B 淋巴细胞凋亡。

作为藏红花中的主要类胡萝卜素,藏红花素具有强大的抗癌作用。然而,它的抗淋巴瘤作用仍然模糊不清,尤其是在人类 EBV 相关的 B 细胞淋巴增殖性疾病中。本研究检查了藏红花素在 CO 88BV59-1 细胞系与正常人外周血 B 细胞中的凋亡潜能及其潜在机制。
更新日期:2021-07-22
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