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Ibrutinib-Associated Cardiovascular Events in a Patient Wearing an Implanted Loop Recorder.
Mediterranean Journal of Hematology and Infectious Diseases ( IF 3.2 ) Pub Date : 2021-07-01 , DOI: 10.4084/mjhid.2021.044
Daniel Rivera 1 , Koichi Takahashi 1 , Jean-Bernard Durand 2 , Alessandra Ferrajoli 1
Affiliation  

Ibrutinib is a well-tolerated and effective therapy used for the treatment of chronic lymphocytic leukemia (CLL). However, its use has been associated with cardiovascular events such as atrial fibrillation (Afib), hypertension, and ventricular arrhythmias. Cardiac arrhythmias represent a significant cause of morbidity and mortality. Implanted loop recorders have been integrated into our clinical practice and have been considered a useful tool in guiding the management of patients with cardiac arrhythmias. We report a case that describes our experience on a patient diagnosed with CLL treated with ibrutinib.

中文翻译:

佩戴植入式环路记录器的患者的依鲁替尼相关心血管事件。

依鲁替尼是一种耐受性良好且有效的疗法,用于治疗慢性淋巴细胞白血病 (CLL)。然而,它的使用与心血管事件有关,例如心房颤动 (Afib)、高血压和室性心律失常。心律失常是发病率和死亡率的重要原因。植入式循环记录仪已被整合到我们的临床实践中,并被认为是指导心律失常患者管理的有用工具。我们报告了一个案例,该案例描述了我们对诊断为 CLL 的患者使用依鲁替尼治疗的经历。
更新日期:2021-07-22
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