PVDF-based membranes with low-fouling and high permeability properties were developed by blending poly(vinylidene fluoride) (PVDF) with poly(2-methoxyethyl acrylate) (PMEA), a low-fouling polymer, via non-solvent induced phase separation (NIPS). Since PMEA suppresses protein adsorption and is insoluble in water, the PMEA homopolymer was used as an additive. Consequently, transparent dope solutions containing 15 wt% PVDF and 0–7 wt% PMEA were prepared using N-methyl-2-pyrrolidone as the solvent. The macrovoids in the blended membranes were larger than those in the pristine PVDF membrane and were probably attributed to the PMEA-promoted solvent exchange during the NIPS process. As a result, the pure water permeabilities of the blended membranes were 5–10 times higher than those of the pristine PVDF membrane. The ATR FT-IR characterization revealed that the PMEA composition of the membrane surfaces increased as the PMEA blend ratio in the dope solution increased. This resulted in the improvement of their low-fouling properties when used in 1000 ppm of bovine serum albumin (BSA) and lysozyme aqueous solutions. Additionally, the PMEA-blended PVDF membrane with the highest PMEA ratio showed the best low-fouling properties.

通过将聚偏二氟乙烯 (PVDF) 与聚丙烯酸 2-甲氧基乙酯 (PMEA)（一种低污染聚合物）混合，通过非溶剂诱导相分离，开发出具有低污染和高渗透性的 PVDF 膜。 NIPS）。由于 PMEA 抑制蛋白质吸附且不溶于水，因此使用 PMEA 均聚物作为添加剂。因此，使用N制备含有 15 wt% PVDF 和 0–7 wt% PMEA 的透明涂料溶液-甲基-2-吡咯烷酮作为溶剂。混合膜中的大孔隙比原始 PVDF 膜中的大，这可能归因于 NIPS 过程中 PMEA 促进的溶剂交换。结果，混合膜的纯水渗透率是原始 PVDF 膜的 5-10 倍。ATR FT-IR 表征表明，随着涂料溶液中 PMEA 混合比例的增加，膜表面的 PMEA 组成增加。当在 1000 ppm 的牛血清白蛋白 (BSA) 和溶菌酶水溶液中使用时，这导致它们的低污染特性得到改善。此外，具有最高 PMEA 比率的 PMEA 混合 PVDF 膜显示出最好的低污染性能。