The use of vegetable oils in lipid nanoparticle preparation is a promising field for treating diverse pathologies. Developing these particles requires advanced knowledge of formulation design, preparation techniques, product stability, and proof of concept using performance tests. This review explores the most recent studies on the application of vegetable oils in developing lipid-based nanocarriers. A PubMed search was carried out covering studies of up to 10 years. Topics discussed herein include formulation development and preparation methods, in addition to in vitro and in vivo performance tests. The studies have shown superior efficacy of lipid-based nanocarriers containing vegetable oils compared to the commercial therapy, which highlights their promising use in nanotechnology aiming to provide safer and more effective pharmaceutical and cosmetic products.

在脂质纳米颗粒制备中使用植物油是治疗多种病理的有前途的领域。开发这些颗粒需要有关配方设计、制备技术、产品稳定性和使用性能测试的概念验证的高级知识。本综述探讨了植物油在开发基于脂质的纳米载体中的应用的最新研究。进行了一项涵盖长达 10 年的研究的 PubMed 搜索。除了体外和体内性能测试外，本文讨论的主题还包括配方开发和制备方法。研究表明，与商业疗法相比，含有植物油的基于脂质的纳米载体具有更好的疗效，