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Tpt1 the balance toward immunosuppression upon cell death
Nature Immunology ( IF 30.5 ) Pub Date : 2021-07-19 , DOI: 10.1038/s41590-021-00986-2
Yuting Ma 1, 2
Affiliation  

By engaging Toll-like receptor 2, translationally controlled tumor protein (TCTP) released from necrotic tumor cells can switch on an immunosuppressive network of monocytic and polymorphonuclear myeloid-derived suppressor cells to block antitumor immunity.

中文翻译:

Tpt1 细胞死亡时免疫抑制的平衡

通过与 Toll 样受体 2 结合,从坏死肿瘤细胞释放的翻译控制的肿瘤蛋白 (TCTP) 可以打开单核细胞和多形核髓源性抑制细胞的免疫抑制网络,以阻断抗肿瘤免疫。
更新日期:2021-07-20
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