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Complex dynamics of multicomponent biological coacervates
Current Opinion in Colloid & Interface Science ( IF 8.9 ) Pub Date : 2021-07-20 , DOI: 10.1016/j.cocis.2021.101488
Jenna K.A. Tom 1 , Ashok A. Deniz 1
Affiliation  

Phase transitions and coacervates play key roles in natural and synthetic soft matter. In particular, the past few years have seen a rapid expansion in studies of these phenomena in the context of dynamic cellular compartmentalization. In this brief review, we mainly focus on a few concepts and selected in vitro and cellular examples of recent developments in the areas of dynamics and multicomponent systems. Topics covered include the flexibility and conformational dynamics of polymeric species involved in phase separation, valence and non-monotonic effects, noise modulation and feedback loops, and multicomponent systems and substructure. The fundamental concepts discussed in this review are widely applicable, including in the context of cellular function and the development of materials with novel properties.



中文翻译:

多组分生物凝聚层的复杂动力学

相变和凝聚层在天然和合成软物质中起着关键作用。特别是,在过去的几年里,在动态细胞区室化的背景下,对这些现象的研究迅速扩大。在这篇简短的评论中,我们主要关注一些概念,并选择了动力学和多组分系统领域最新发展的体外和细胞示例。涵盖的主题包括涉及相分离、价态和非单调效应、噪声调制和反馈回路以及多组分系统和子结构的聚合物物种的灵活性和构象动力学。本综述中讨论的基本概念具有广泛的适用性,包括在细胞功能的背景下和具有新特性的材料的开发。

更新日期:2021-08-31
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