Due to the natural dispersity that is present in synthetic polymers, an added complexity is always present in the analysis of polymeric species. Tandem mass spectrometry analysis requires the isolation of individual precursors before a fragmentation event to allow the unambiguous characterization of these species and is not viable at certain levels of complexity due to achievable isolation widths. Two-dimensional mass spectrometry (2DMS) fragments ions and correlates fragments with their corresponding precursors without the need for isolation. In this study, 2DMS electron capture dissociation (ECD) fragmentation of a polyoxazoline and polyacrylamide species was carried out, resulting in the analysis of byproducts and individual polymer species without the use of chromatographic techniques. This study shows that 2DMS ECD is a powerful tool for the analysis of polyacrylamide and polyoxazoline species and offers a new dimension in the characterization of polymers.

中文翻译：

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分散性表征：二维聚合物质谱。

由于合成聚合物中存在的天然分散性，聚合物种类的分析总是存在额外的复杂性。串联质谱分析需要在碎裂事件之前分离单个前体，以明确表征这些物质，并且由于可实现的分离宽度，在某些复杂程度下是不可行的。二维质谱 (2DMS) 将离子碎片化并将碎片与其相应的前体相关联，而无需进行分离。在这项研究中，对聚恶唑啉和聚丙烯酰胺物质进行了 2DMS 电子捕获解离 (ECD) 裂解，从而在不使用色谱技术的情况下分析了副产物和单个聚合物物质。