Purpose: Few studies have examined menstrual differences between patients with anorexia nervosa (AN) versus avoidant/restrictive food intake disorder (ARFID). After observing that many patients with ARFID maintain regular menses despite weight loss, we sought to characterize these menstrual differences in the context of specific eating behaviors.

Methods: Patients with AN or ARFID in a disordered eating database at the University of Oklahoma Health Sciences Center were included. Bivariate analyses explored group differences in demographics, age, percentage of median body mass index for age (%mBMI), time since last menstrual period (LMP), and reported eating behaviors, including whether self-reported diet history included “junk food” consumption in the past 24 hours. Regression analysis examined whether diagnosis and variables that were associated with diagnosis significantly predicted time since LMP.

Results: The analyses included 89 participants diagnosed with AN or ARFID (AN: n = 70; ARFID: n = 19). The AN group had higher %mBMI for age than the ARFID group (83.4% vs 76.4%, respectively, P = .004) and was less likely to have reported consuming junk food the day prior (36.8% vs 76.5%, respectively, P = .003). Time since LMP was longer for those with AN versus ARFID (174 vs 13 days, respectively, P < .0001). A 2-predictor model with diagnosis and junk food explained a significant proportion of variance in time since LMP (P = .012).

Conclusion: This paper may be the first to describe menstrual differences among individuals with AN and ARFID in the context of eating behaviors. In addition to diagnosis, having no self-reported junk food consumption in the past 24 hours was significantly associated with longer time since LMP. Studies that include specific measures of food intake and hormonal responses to food quality are warranted to further explore the etiology of menstrual differences among patients with AN and ARFID.

目的：很少有研究检查神经性厌食症 (AN) 与回避/限制性食物摄入障碍 (ARFID) 患者之间的月经差异。在观察到许多 ARFID 患者尽管体重减轻但仍保持规律的月经后，我们试图在特定饮食行为的背景下表征这些月经差异。

方法：包括俄克拉荷马大学健康科学中心饮食失调数据库中的 AN 或 ARFID 患者。双变量分析探讨了人口统计学、年龄、年龄体重指数中位数百分比 (%mBMI)、自上次月经以来的时间 (LMP) 和报告的饮食行为（包括自我报告的饮食史是否包括“垃圾食品”消费）的组差异在过去的 24 小时内。回归分析检查诊断和变量是否与自 LMP 以来的显着预测时间相关。

结果：分析包括 89 名大小为 AN 或 ARFID 的参与者（AN：n = 70；ARFID：n = 19）。AN 组的年龄 mBMI 百分比高于 ARFID 组（分别为 83.4% 和 76.4%，P  = .004）并且报告前一天食用垃圾食品的可能性较小（分别为 36.8% 和 76.5%，P  = .003）。AN 患者与 ARFID 患者的 LMP 时间更长（分别为 174 天和 13 天，P < .0001）。带有诊断和垃圾食品的 2 预测器模型解释了自 LMP 以来的显着时间变化比例 ( P  = .012)。

结论：本文可能是第一个在饮食行为背景下描述 AN 和 ARFID 患者月经差异的论文。除了诊断外，过去 24 小时内没有自我报告的垃圾食品消费与自 LMP 以来更长的时间显着相关。有必要进行包括食物摄入和激素对食物质量反应的具体测量的研究，以进一步探索 AN 和 ARFID 患者月经差异的病因。