Abstract

A simple and efficient protocol for the synthesis of benzimidazolylimidazo[4,5-b]indoles has been developed through the condensation of 2-aminobenzimidazole, aromatic aldehyde, ammonium acetate, and isatin via multicomponent reaction strategy using ceric ammonium nitrate as catalyst. The key advantages of the four-component reaction are easy work-up, high yield, short reaction time, and environmentally safe solvent.

中文翻译：

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在乙醇水溶液中硝酸铈铵催化新型 2-Aryl-3-benzimidazolyl-3,4-dihydroimidazo[4,5-b]indoles 的简单高效四组分一锅法合成

摘要

通过使用硝酸铈铵作为催化剂的多组分反应策略，通过 2-氨基苯并咪唑、芳香醛、乙酸铵和靛红的缩合，开发了一种简单有效的合成苯并咪唑基咪唑并[4,5- b ]吲哚的方案。四组分反应的主要优点是后处理容易、收率高、反应时间短和溶剂环保。