Cosmeceuticals are cosmetic products containing biologically active ingredients with attractive properties (e.g. anti-oxidant, anti-inflammatory, anti-aging, photoprotective activity, etc.). The aim of these compounds is to offer pharmaceutically therapeutic benefits. The active ingredients can be extracted and purified from natural sources, including plants and animals, or be obtained by biotechnological methodologies (e.g. fermentation, enzymatic synthesis, etc.). Recent years have been increased interest in the design and development of bioactive compounds with cosmeceutical applications and low toxicity. The enzymatic synthesis of bioactive esters, based on esterification or transesterification, has attracted much interest because of the interesting properties of the resulting products and because, by replacing traditional chemical catalysts, this approach leads towards the development of more sustainable processes that follow the principles of Green Chemistry. This review gives an overview of the excellent suitability of lipases as biocatalysts for producing bioactive compounds with attractive properties for the cosmetics industry.

药妆品是含有具有吸引力的生物活性成分（例如抗氧化、抗炎、抗衰老、光保护活性等）的化妆品。这些化合物的目的是提供药物治疗益处。活性成分可以从包括植物和动物在内的天然来源中提取和纯化，或者通过生物技术方法（例如发酵、酶促合成等）获得。近年来，人们对具有药妆应用和低毒性的生物活性化合物的设计和开发越来越感兴趣。基于酯化或酯交换的生物活性酯的酶促合成引起了很多兴趣，因为所得产品具有有趣的特性，并且因为通过替代传统的化学催化剂，这种方法导致遵循绿色化学原则的更可持续的过程的发展。本综述概述了脂肪酶作为生物催化剂的优异适用性，可用于生产对化妆品行业具有吸引力的生物活性化合物。