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Why Remdesivir Failed: Preclinical Assumptions Overestimate the Clinical Efficacy of Remdesivir for COVID-19 and Ebola
Antimicrobial Agents and Chemotherapy ( IF 4.9 ) Pub Date : 2021-07-12 , DOI: 10.1128/aac.01117-21
Victoria C Yan 1 , Florian L Muller 2
Affiliation  

Remdesivir is a nucleoside monophosphoramidate prodrug that has been FDA-approved for COVID-19. However, the clinical efficacy of remdesivir for COVID-19 remains contentious, as several trials have not found statistically significant differences in either ...

中文翻译:

为什么瑞德西韦失败:临床前假设高估了瑞德西韦对 COVID-19 和埃博拉的临床疗效

瑞德西韦是一种核苷单磷酰胺前药,已获得 FDA 批准用于 COVID-19。然而,remdesivir 对 COVID-19 的临床疗效仍然存在争议,因为几项试验没有发现两者在统计学上的显着差异......
更新日期:2021-09-12
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