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Assessing the utility of screening electrocardiograms in paediatric patients following COVID-19
Cardiology in the Young ( IF 1 ) Pub Date : 2021-07-08 , DOI: 10.1017/s1047951121003012
Ari J Gartenberg 1 , Travus J White 1 , Khoi Dang 2 , Maully Shah 1 , Stephen M Paridon 1 , Matthew D Elias 1
Affiliation  

Objective:

To determine the utility of screening electrocardiograms after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among children in detecting myocarditis related to coronavirus disease 2019 (COVID-19).

Study Design:

A retrospective chart review was performed at a large paediatric academic institution to identify patients with prior SARS-CoV-2 infection who received a screening electrocardiogram by their primary care providers and were subsequently referred for outpatient cardiology consultation due to an abnormal electrocardiogram. The outcomes were the results from their cardiology evaluations, including testing and final diagnoses.

Results:

Among 46 patients, during their preceding COVID-19 illness, the majority had mild symptoms, 4 were asymptomatic, and 1 had moderate symptoms. The median length of time from positive SARS-CoV-2 test to screening electrocardiogram was 22 days, and many electrocardiogram findings that prompted cardiology consultation were normal variants in asymptomatic adolescent athletes. Patients underwent frequent additional testing at their cardiology appointments: repeat electrocardiogram (72%), echocardiogram (59%), Holter monitor (11%), exercise stress test (7%), and cardiac MRI (2%). Five patients were incidentally diagnosed with CHD or structural cardiac abnormalities, and three patients had conduction abnormalities (pre-mature atrial contractions, pre-mature ventricular contractions, borderline prolonged QTc), although potentially incidental to COVID-19. No patients were diagnosed with myocarditis or ventricular dysfunction.

Conclusion:

In a small cohort of children with prior COVID-19, who were primarily either asymptomatic or mildly symptomatic, subsequent screening electrocardiograms identified various potential abnormalities prompting cardiology consultation, but no patient was diagnosed with myocarditis. Larger multi-centre studies are necessary to confirm these results and to evaluate those with more severe disease.



中文翻译:

评估筛查心电图对 COVID-19 后儿科患者的效用

客观的:

确定在儿童感染严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2) 后筛查心电图在检测与 2019 年冠状病毒病 (COVID-19) 相关的心肌炎中的效用。

学习规划:

在一家大型儿科学术机构进行了回顾性图表审查,以确定先前感染过 SARS-CoV-2 的患者,这些患者接受了初级保健提供者的心电图筛查,随后由于心电图异常而被转诊至门诊心脏病科会诊。结果是他们的心脏病学评估结果,包括测试和最终诊断。

结果:

在 46 名患者中,在他们之前的 COVID-19 疾病期间,大多数有轻微症状,4 名无症状,1 名有中度症状。从 SARS-CoV-2 检测呈阳性到筛查心电图的中位时间为 22 天,许多提示心脏病学咨询的心电图结果在无症状青少年运动员中是正常变异。患者在心脏科就诊时经常接受额外的检查:重复心电图 (72%)、超声心动图 (59%)、动态心电图 (11%)、运动负荷测试 (7%) 和心脏 MRI (2%)。5 名患者被偶然诊断为 CHD 或结构性心脏异常,3 名患者出现传导异常(房性早搏、心室早搏、QTc 临界延长),尽管可能与 COVID-19 相关。

结论:

在一小群先前患有 COVID-19 的儿童中,他们主要是无症状或轻度症状,随后的筛查心电图发现了各种潜在的异常,提示心脏病科会诊,但没有患者被诊断出患有心肌炎。需要更大规模的多中心研究来证实这些结果并评估那些患有更严重疾病的人。

更新日期:2021-07-08
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